Searchable abstracts of presentations at key conferences in endocrinology

ea0049oc9.3 | Thyroid Disease 2 | ECE2017

How much of the genetic predisposition to Hashimoto’s thyroiditis can be explained by genes commonly associated with the disease?

Skalniak Anna , Jabrocka-Hybel Agata , Piętkowski Jakub , Turek-Jabrocka Renata , Pach Dorota , Ludwig-Gałęzowska Agnieszka , Machlowska Julita , Kapusta Przemysław , Wołkow Paweł , Hubalewska-Dydejczyk Alicja

Background: Hashimoto’s thyroiditis (HT) is a common autoimmune disorder of the thyroid (AITD) which affects about 1–2% of the European population. The disease often clusters in families, which is why many attempts have been undertaken to find the genetic background that would underly the predisposition to HT. In contrast to another AITD - Graves’ disease, results of genetic analyses have been ambiguous and have failed to find a major genetic locus that would be...